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Kalehua Capital Management LLC

CIK 2106181 · latest 13F filed 19 August 2026 · Read the filing on EDGAR

Kalehua Capital Management LLC reported 26 US-listed holdings worth $313.5 million in its 13F for the quarter ended 30 June 2026, filed 19 August 2026. Its largest: Veradermics Inc (11.4%), X4 Pharmaceuticals Inc. (11.1%) and Ea Series Trust (8.4%). Against the quarter before, it opened 8 positions, added to 5, trimmed 3 and sold out of 7.

Reported holdings$313.5M+20.6% on Q1 2026
Positions26+1 on Q1 2026
The largest ten70.1%of its reported holdings
Latest 13FQ2 2026filed 19 August 2026
Where the money is
OpenedAdded toHeldTrimmed
MANE11.4%XFOR11.1%BOXX8.4%CMPS7.4%SRZN6.4%ACRS6.2%SION5.5%IKT4.9%PHVS4.4%KPTI4.3%SEPN4.2%IFRX4.1%CYCN3.6%12 more15.7%

The 14 largest of its 26 positions, each sized by its share of the reported holdings, coloured by the change in shares against Q1 2026.

Reported holdings, quarter by quarter
Q4 2025: $101.1 million in 19 positions$101MQ4 25Q1 2026: $259.9 million in 25 positions$260MQ1 26Q2 2026: $313.5 million in 26 positions$313MQ2 26

What the fund reported holding at each quarter's end; hover a bar for the number of positions

What its reported holdings returned

Held through each quarter, the holdings it reported returned +43.8% over the 2 quarters to 30 June 2026, against +9.5% for the S&P 500.

Its reported holdingsThe S&P 500
90105120135Q4 25Q1 26Q2 26Its holdings +43.8%S&P 500 +9.5%

Not the fund's own return: each 13F's holdings are kept unchanged until the next one, so trades inside a quarter, dividends, cash and fees are left out. A rough guide to how its picks have done over time.

What it did on the quarter

Opened 8Added 5Held 10Trimmed 3Sold out 7
Opened: 8Added: 5Held: 10Trimmed: 3Sold out: 7

Its positions against its 13F for the quarter to 31 March 2026; a change under 0.1% of a position counts as held

Opened 8

  1. Karyopharm Therapeutics Inc. KPTI$13.4 million
  2. Inflarx NV IFRX$13.0 million
  3. Cyclerion Therapeutics Inc. CYCN$11.2 million
  4. Nuvectis Pharma Inc. NVCT$3.7 million
  5. Milestone Pharmaceuticals Inc. (mist) MIST$3.4 million
  6. Adlai Nortye Ltd ANL$2.6 million
  7. Atyr Pharma Inc. ATYR$2.1 million
  8. Tscan Therapeutics Inc. TCRX$891,648

Added to 5

  1. Veradermics Inc MANE+42,816 shares · +17%
  2. Korro Bio Inc. KRRO+295,664 shares · +270%
  3. Aclaris Therapeutics Inc. ACRS+494,809 shares · +16%
  4. Inhibikase Therapeutics Inc. IKT+1.1 million shares · +18%
  5. Gossamer Bio Inc. GOSS+4.6 million shares · +26%

Trimmed 3

  1. Uniqure NV QURE-343,997 shares · -68%
  2. Ea Series Trust BOXX-110,512 shares · -33%
  3. Instil Bio Inc. TIL-123,679 shares · -38%

Sold out of 7

  1. Relay Therapeutics Inc. RLAY$17.9 million last quarter
  2. Oruka Therapeutics Inc. ORKA$11.6 million last quarter
  3. Pepgen Inc. PEPG$3.1 million last quarter
  4. Tenaya Therapeutics Inc. TNYA$2.8 million last quarter
  5. Kalaris Therapeutics Inc KLRS$1.6 million last quarter
  6. Diamedica Therapeutics Inc. DMAC$846,088 last quarter
  7. Loop Industries Inc. LOOP$361,441 last quarter

What it holds

CompanySharesValueOf its bookChange in shares
Veradermics Inc MANE291.4K$35.8 million11.43%+42.8K
X4 Pharmaceuticals Inc. XFOR7.4M$34.8 million11.09%no change
Ea Series Trust BOXX226.2K$26.5 million8.45%-110.5K
Compass Pathways PLC CMPS1.6M$23.2 million7.40%no change
Surrozen Inc. SRZN770.4K$20.0 million6.38%no change
Aclaris Therapeutics Inc. ACRS3.7M$19.4 million6.18%+494.8K
Sionna Therapeutics Inc SION394.1K$17.3 million5.53%no change
Inhibikase Therapeutics Inc. IKT7.6M$15.5 million4.95%+1.1M
Pharvaris N V PHVS397.5K$13.7 million4.39%no change
Karyopharm Therapeutics Inc. KPTI1.4M$13.4 million4.27%new
Septerna Inc. SEPN389.1K$13.0 million4.16%no change
Inflarx NV IFRX5.8M$13.0 million4.14%new
Cyclerion Therapeutics Inc. CYCN3.3M$11.2 million3.57%new
Uniqure NV QURE158.8K$7.3 million2.33%-344.0K
Athira Pharma Inc. LONA787.4K$7.2 million2.31%no change
Galecto Inc. DMRA278.0K$7.2 million2.31%no change
Moonlake Immunotherapeutics MLTX351.5K$6.8 million2.18%no change
Korro Bio Inc. KRRO405.0K$5.3 million1.70%+295.7K
Tyra Biosciences Inc. TYRA148.9K$4.8 million1.52%no change
Nuvectis Pharma Inc. NVCT200.0K$3.7 million1.17%new
Gossamer Bio Inc. GOSS22.3M$3.7 million1.17%+4.6M
Milestone Pharmaceuticals Inc. (mist) MIST2.5M$3.4 million1.09%new
Adlai Nortye Ltd ANL226.4K$2.6 million0.83%new
Atyr Pharma Inc. ATYR3.6M$2.1 million0.68%new
Instil Bio Inc. TIL199.2K$1.5 million0.49%-123.7K
Tscan Therapeutics Inc. TCRX909.8K$891,6480.28%new
Every US-listed position in the fund's 13F for the quarter ended 30 June 2026, by the value it reported.
Read moreChange is shares against its 13F for the quarter before; the 7 it sold out of are in the box above.