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Edwards Lifesciences Corp.: Q4 FY2025 earnings call

What management said about Q4 FY2025, from the documents filed with the SEC on 10 February 2026: press release. Guidance figures: 2 kept. The quarter’s numbers.

Key takeaways

  • Q4 sales grew 13.3% reported: Fourth-quarter sales were $1.57 billion, up 13.3% reported and 11.6% in constant currency. Full-year 2025 sales grew 11.5%, or 10.7% in constant currency. Source
  • Q4 EPS $0.11 GAAP, $0.58 adjusted: Diluted EPS from continuing operations was $0.11 for the quarter and adjusted EPS was $0.58. Full-year 2025 adjusted diluted EPS was $2.56 per the reconciliation tables. Source
  • TAVR sales grew 12.0% in Q4: TAVR sales were $1.16 billion, up 12.0% reported and 10.6% in constant currency. Full-year 2025 global TAVR sales were $4.5 billion, up 8.6% in constant currency. Source
  • TMTT sales grew over 40% in Q4: TMTT sales were $156 million in the quarter. Global adoption of PASCAL and EVOQUE contributed, and the company continues to expand centers and physician training. Source
  • SAPIEN M3 launch starts at ENCIRCLE sites: Edwards is initially opening sites that were previously in the ENCIRCLE pivotal trial. Management said physician focus and interest in the technology is growing. Source
  • SG&A rose to 38.4% of sales: SG&A was $603 million, or 38.4% of sales, against 35.5% a year earlier. Management attributed the increase to investment to amplify patient access to therapy. Source
  • Operating margin met quarterly guidance: Operating margin was 9.6% reported and 23.7% adjusted, in line with the mid-20% guidance given for the quarter. Adjusted EPS also included a higher-than-expected tax rate. Source
  • Long-term trial data cited as catalysts: Management cited PARTNER 3 7-year and PARTNER 2 10-year results, EARLY TAVR, European guidelines and the first transcatheter mitral replacement approval as enduring catalysts into 2026. Source

“We expect additional meaningful catalysts later in 2026 to fuel sustainable growth into the future”

Bernard Zovighian, Edwards’ CEO

Guidance

AreaPeriodFigureAgainst last quarter
Constant-currency sales growth SourceFY 20268 to 10%
Adjusted EPS SourceFY 2026$2.90 to $3.05
Adjusted gross profit margin SourceFY 202678% to 79%Kept
R&D as a percentage of sales SourceFY 2026approximately 17%Kept
Operating profit margin SourceFY 2026high end of 28% to 29%
Total sales SourceQ1 2026$1.55 to $1.63 billion
Adjusted EPS SourceQ1 2026$0.70 to $0.76

What changed from last quarter

  • New: The U.S. FDA approved SAPIEN M3 for mitral replacement, the first transcatheter replacement option for mitral disease in the U.S. Source
  • New: CMS formally opened a process to reconsider the National Coverage Determination for TAVR. Source
  • New: Edwards expanded its American Heart Association partnership by becoming founding sponsor of a multi-year Heart Valve Initiative. Source

Results and growth drivers

  • Q4 sales grew 13.3% reported: Fourth-quarter sales were $1.57 billion, up 13.3% reported and 11.6% in constant currency. Full-year 2025 sales grew 11.5%, or 10.7% in constant currency. Source
  • Q4 EPS $0.11 GAAP, $0.58 adjusted: Diluted EPS from continuing operations was $0.11 for the quarter and adjusted EPS was $0.58. Full-year 2025 adjusted diluted EPS was $2.56 per the reconciliation tables. Source
  • Litigation expenses rose sharply: Intellectual property and litigation expenses were $208.6 million in the fourth quarter, against $12.6 million a year earlier. Full-year 2025 such expenses totaled $325.4 million. Source
  • Regional growth varied by region: U.S. sales rose 11.6%. Europe rose 19.1% reported and 11.9% in constant currency, Japan 1.9% and 3.9%, and Rest of World 15.5% and 15.9%. Source

TAVR sales and evidence

  • TAVR sales grew 12.0% in Q4: TAVR sales were $1.16 billion, up 12.0% reported and 10.6% in constant currency. Full-year 2025 global TAVR sales were $4.5 billion, up 8.6% in constant currency. Source
  • U.S. and outside U.S. grew alike: Constant-currency growth was similar in the U.S. and outside the U.S. Procedure growth was comparable across both, and average price and competitive position were stable globally. Source
  • Europe share improved after exit: In Europe, management said it continues to see modest year-over-year share improvement following a competitor's exit, alongside healthy underlying procedure growth. Source
  • Earlier treatment of severe aortic stenosis: Management described intentional and urgent treatment of severe aortic stenosis patients in the U.S., supported by growing evidence on the SAPIEN platform. Source

“our differentiated strategy with a clear vision around three key elements: focusing solely on structural heart”

Bernard Zovighian, Edwards’ CEO

TMTT growth and new launches

  • TMTT sales grew over 40% in Q4: TMTT sales were $156 million in the quarter. Global adoption of PASCAL and EVOQUE contributed, and the company continues to expand centers and physician training. Source
  • Full-year TMTT sales up 56%: Full-year 2025 TMTT sales were $550.6 million, up 56.4% reported and 53.1% in constant currency, as set out in the product group reconciliation. Source
  • SAPIEN M3 launch starts at ENCIRCLE sites: Edwards is initially opening sites that were previously in the ENCIRCLE pivotal trial. Management said physician focus and interest in the technology is growing. Source

Surgical and product pipeline

  • Surgical sales up 4% in Q4: Fourth-quarter Surgical sales from continuing operations were $254 million, up 4% reported and 2% in constant currency. Full-year Surgical sales topped $1 billion, up 5%. Source
  • RESILIA therapies drove surgical growth: Management attributed Surgical growth to adoption of RESILIA therapies, which it said offer extended durability, including INSPIRIS, KONECT and MITRIS. Source
  • Left atrial appendage closure in development: Edwards is pursuing several new surgical innovations, including left atrial appendage closure, which management described as complementary to specific valvular procedures. Source

Costs, margins and R&D spending

  • Gross margin slightly lower year over year: Q4 gross profit margin was 78.1% reported and 78.3% adjusted, compared with 78.9% and 79.0% adjusted a year earlier. Full-year 2025 adjusted gross margin was 78.1%. Source
  • SG&A rose to 38.4% of sales: SG&A was $603 million, or 38.4% of sales, against 35.5% a year earlier. Management attributed the increase to investment to amplify patient access to therapy. Source
  • R&D fell to 17.1% of sales: R&D expense was $268 million, or 17.1% of sales, against 19.6% a year earlier. Full-year 2025 R&D was 17.8% of sales. Source
  • Operating margin met quarterly guidance: Operating margin was 9.6% reported and 23.7% adjusted, in line with the mid-20% guidance given for the quarter. Adjusted EPS also included a higher-than-expected tax rate. Source

Cash, debt and share count

  • Cash about $3.0 billion, debt $600 million: Cash and cash equivalents were approximately $3.0 billion at December 31, 2025. Total debt was approximately $600 million. Source
  • Diluted share count declined: Q4 diluted weighted-average shares were 581.8 million, against 590.5 million a year earlier. Full-year 2025 diluted weighted-average shares were 585.8 million. Source
  • Net interest income rose in 2025: Interest income, net was $35.9 million in Q4 against $44.2 million a year earlier. Full-year 2025 interest income, net was $148.4 million against $100.5 million. Source

Strategy, evidence and catalysts

  • Structural heart focus and innovation: Management described the strategy as focusing solely on structural heart, solving large, urgent and very complex patient needs, and pursuing unique innovation. Source
  • Long-term trial data cited as catalysts: Management cited PARTNER 3 7-year and PARTNER 2 10-year results, EARLY TAVR, European guidelines and the first transcatheter mitral replacement approval as enduring catalysts into 2026. Source
  • European guidelines reshape TAVR discussions: Updated European guidelines are reshaping clinical discussions around proactive disease management and reinforcing TAVR for a broader patient population, management said. Source

Coming up, as management said on 10 February 2026

  • Later-2026 catalysts expected: Management expects further catalysts later in 2026: next-generation TEER, PASCAL for U.S. tricuspid patients, continued scaling of EVOQUE, and possible access gains from an updated TAVR NCD. Source
  • Surgical LAAC introduction later this year: A preliminary introduction of a new surgical left atrial appendage closure technology is planned for later this year. Source

Risks management discussed

  • Financial: Intellectual property litigation, settlements and legal costs are recorded as expenses and reduced fourth-quarter operating income. Source
  • Financial: A $99.8 million impairment of the JenaValve Technologies investment is reported below operating income in GAAP results. Source

Earlier plans management reported on

  • Met: Management said the Q4 operating margin of 9.6% reported and 23.7% adjusted was in line with the earlier mid-20% guidance for the quarter. Source
  • Delayed: Part of the strategic spending had been planned for earlier quarters, and management said it was delayed into the fourth quarter. Source

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.