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Artivion, Inc.: Q4 FY2025 earnings call

What management said about Q4 FY2025, from the documents filed with the SEC on 12 February 2026: press release. Guidance figures: 2 new, 1 kept. The quarter’s numbers.

Key takeaways

  • Full-year revenue rose to $441.3 million: Full-year GAAP revenue was $441.3 million versus $388.5 million in 2024. Adjusted revenue was $443.6 million, up 13% on an adjusted constant currency basis. Source
  • Fourth-quarter revenue reached $116.0 million: GAAP revenue was $116.0 million versus $97.3 million a year earlier. Adjusted revenue of $118.3 million rose 18% on an adjusted constant currency basis. Source
  • Aortic stent grafts led fourth-quarter growth: Stent graft revenue was $43.3 million in the fourth quarter, up 44% as reported and 36% on an adjusted constant currency basis. Full-year stent grafts reached $159.4 million. Source
  • Adjusted EBITDA rose 26% for the year: Adjusted EBITDA was $22.7 million in the fourth quarter, up 29% from $17.6 million. Full-year adjusted EBITDA was $89.6 million, up 26% from $71.3 million. Source
  • Operating cash flow rose for the year: Net cash from operating activities was $39.9 million for 2025 versus $22.2 million in 2024. Free cash flow, a non-GAAP measure, was $0.8 million for the year and $(7.9) million in the fourth quarter. Source
  • Endospan NEXUS data presented at STS: Positive new clinical data from Endospan’s NEXUS TRIOMPHE IDE trial were presented at the STS Annual Meeting, showing 94% survival from lesion-related death at one year. Source
  • AMDS PMA submission completed: The company filed the fourth and final module of the pre-market approval application with the FDA for the AMDS Hybrid Prothesis. Source

“We are very pleased with our strong performance for the full year 2025 as we drove 13% adjusted constant currency revenue growth and 26% adjusted EBITDA growth”

Pat Mackin, Chairman, President, and Chief Executive Officer

Guidance

AreaPeriodFigureAgainst last quarter
Revenue Sourcefull year 2026$486 to $504 millionNew
Adjusted EBITDA Sourcefull year 2026$105 to $110 millionNew
Long-term growth Sourcelong-termdouble-digit constant currency revenue growth; adjusted EBITDA growth at twice that paceKept

What changed from last quarter

  • New guidance: Full-year 2026 revenue and adjusted EBITDA guidance was given in this release; the prior release gave guidance for 2025 only. Source

Results and growth drivers

  • Full-year revenue rose to $441.3 million: Full-year GAAP revenue was $441.3 million versus $388.5 million in 2024. Adjusted revenue was $443.6 million, up 13% on an adjusted constant currency basis. Source
  • Fourth-quarter revenue reached $116.0 million: GAAP revenue was $116.0 million versus $97.3 million a year earlier. Adjusted revenue of $118.3 million rose 18% on an adjusted constant currency basis. Source
  • Net income was positive after prior-year loss: Fourth-quarter GAAP net income was $2.4 million, or $0.05 per diluted share, compared with a net loss of $(16.5) million a year earlier. Full-year GAAP net income was $9.8 million, or $0.21 per diluted share. Source

Product lines and growth

  • Aortic stent grafts led fourth-quarter growth: Stent graft revenue was $43.3 million in the fourth quarter, up 44% as reported and 36% on an adjusted constant currency basis. Full-year stent grafts reached $159.4 million. Source
  • On-X and preservation services grew: On-X revenue was $27.8 million in the quarter, up 25% as reported and 24% on an adjusted constant currency basis. Preservation services grew 6% to $24.1 million. Source
  • Surgical sealants were flat in the quarter: Surgical sealants revenue was $20.3 million in the fourth quarter, flat on an adjusted constant currency basis, and $76.6 million for the full year. Source

“Entering 2026, we expect to build on our strong financial performance and continued clinical and operational achievements”

Pat Mackin, Chairman, President, and Chief Executive Officer

Revenue by region

  • Europe, Middle East and Africa grew 17%: EMEA fourth-quarter revenue was $39.4 million as reported and $41.7 million adjusted, up 17% on an adjusted constant currency basis. Full-year EMEA revenue was $151.4 million. Source
  • North America grew 18%: North America revenue was $58.1 million in the fourth quarter, up 18% on an adjusted constant currency basis. Full-year North America revenue was $221.7 million. Source
  • Asia Pacific grew 32% in the quarter: Asia Pacific revenue was $12.7 million in the fourth quarter, up 32% on an adjusted constant currency basis. Full-year Asia Pacific revenue was $44.3 million, up 19%. Source
  • Latin America grew 9% in the quarter: Latin America revenue was $5.9 million in the fourth quarter, up 9% on an adjusted constant currency basis. Full-year Latin America revenue was $24.0 million, up 13%. Source

Margins and operating costs

  • Gross margin dollars increased: Gross margin was $73.1 million in the fourth quarter versus $61.5 million a year earlier, and $284.2 million for the full year versus $248.8 million. Source
  • General and administrative expense rose: General, administrative and marketing expense was $56.8 million in the fourth quarter versus $51.4 million. Adjusted G&A, a non-GAAP measure, was $53.5 million versus $47.5 million. Source
  • Business development and cybersecurity items: Business development, integration and severance charges were $5.2 million in the fourth quarter and $7.1 million for the year. Cybersecurity incident was a net recovery of $(2.9) million in the quarter and $4.3 million for the year. Source
  • Interest expense fell year on year: Interest expense was $5.5 million in the fourth quarter versus $9.7 million, and $26.6 million for the full year versus $34.3 million. Interest income was $0.3 million in the quarter. Source
  • Asset sale gains added to operating income: A gain from sale of non-financial assets was recorded: $3.5 million in the fourth quarter and $7.0 million for the year. Operating income was $10.7 million in the quarter versus $2.7 million. Source

Adjusted EBITDA and non-GAAP measures

  • Adjusted EBITDA rose 26% for the year: Adjusted EBITDA was $22.7 million in the fourth quarter, up 29% from $17.6 million. Full-year adjusted EBITDA was $89.6 million, up 26% from $71.3 million. Source
  • Italian reserve excluded from adjusted revenue: A $2.3 million reserve for estimated Italian payback obligations covering fiscal years 2019 through 2025 reduced GAAP revenue and is excluded from adjusted revenue. Source
  • Full-year non-GAAP net income reported: Full-year non-GAAP net income was $29.7 million, or $0.63 per diluted share, versus $10.8 million, or $0.25, in 2024. Fourth-quarter non-GAAP net income was $8.6 million. Source

Cash flow and balance sheet

  • Operating cash flow rose for the year: Net cash from operating activities was $39.9 million for 2025 versus $22.2 million in 2024. Free cash flow, a non-GAAP measure, was $0.8 million for the year and $(7.9) million in the fourth quarter. Source
  • Capital spending increased in 2025: Capital expenditures were $27.5 million in the fourth quarter and $39.0 million for 2025, versus $11.2 million in 2024. Source
  • Long-term debt fell and cash rose: Long-term debt, net was $215.1 million at year end versus $314.2 million. Cash and cash equivalents were $64.9 million versus $53.5 million. Source
  • Stock issuance and Endospan payments: Proceeds from stock option exercises and share issuance were $13.1 million. Payments under Endospan agreements were $8.0 million, against $17.0 million in 2024. Source

Clinical and regulatory milestones

  • Endospan NEXUS data presented at STS: Positive new clinical data from Endospan’s NEXUS TRIOMPHE IDE trial were presented at the STS Annual Meeting, showing 94% survival from lesion-related death at one year. Source
  • AMDS PMA submission completed: The company filed the fourth and final module of the pre-market approval application with the FDA for the AMDS Hybrid Prothesis. Source
  • Two-year AMDS data presented at STS: Two-year data from the AMDS PERSEVERE IDE trial were presented at STS; management said they further demonstrate persistent clinical benefits of the AMDS technology. Source

Risks management discussed

  • Regulatory: Italian legislation could require repayment of previously paid amounts where spending exceeds regional ceilings, according to the company's footnote description. Source
  • Financial: Management said excluded items, such as non-cash compensation and potential charges or gains, could have a material impact on GAAP measures. Source

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.