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Alnylam Pharmaceuticals (ALNY) Q3 FY2026 earnings: revenue $1.5 billion, up 16.7% on the year

Alnylam Pharmaceuticals, Inc. (ALNY) reported revenue of $1.5 billion for Q3 FY2026, the quarter ended 30 September 2026, up 16.7% on the same quarter a year earlier. Net income was $2.2 billion, up 640.5% on the year as the company restated it, and diluted earnings per share $15.72. The figures are the company's own, from the 10-Q it filed with the SEC on 29 October 2026.

Revenue$1.5 billionup 16.7%
Net income$2.2 billionup 640.5% on the restated year
Diluted EPS$15.72
QuarterQ3 FY2026ended 30 September 2026

What management said

Guidance figures: 8 kept.

  • Net product revenues rose 52 percent: Net product revenues were $1,292 million against $851 million, with TTR at $1,150 million and Rare at $142 million.
  • AMVUTTRA drove TTR growth: AMVUTTRA reached $1,130 million, up 65% (66% at constant exchange rates). ONPATTRO fell to $20 million from $39 million, down 50%.
  • U.S. TTR revenue bridge from Q2: U.S. TTR revenue rose $99 million on the quarter: demand added $81 million, an inventory benefit $17 million, and net price a modest increase, with about $10 million from gross-to-net adjustments.
Read the earnings call summary

The quarter, against the one before and a year earlier

LineQ3 FY2026Q2 FY2026Q3 FY2025Change on the year
Revenue1,4581,2911,249+16.7%
Cost of revenue362298197+83.4%
Gross profit1,0969931,052+4.2%
Gross margin75.2%76.9%84.2%
Research and development409413359+13.9%
Selling, general and administrative342348322+6.2%
Operating income346231368-6.0%
Operating margin23.7%17.9%29.5%
Interest expense84.482.144.4+90.0%
Pre-tax income296178239+23.8%
Income tax-1,87213.3-12.1n/a
Effective tax rate-632.7%7.5%-5.1%
Net income2,167164251+763.2%
Net margin148.6%12.7%20.1%
Diluted EPS$15.72$1.21$1.84+754.3%
$ million except per share.
Read moreFree cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Those four are arithmetic on the filed numbers; everything else is as filed. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and share counts are as they are.

Cash flow and capital returned

LineQ3 FY2026Q2 FY2026Q3 FY2025Change on the year
Operating cash flow341327325+4.9%
Capital expenditure69.834.712.1+475.1%
Free cash flow271292313-13.4%
Free cash flow margin18.6%22.6%25.1%
Cash from investing-312-363501n/a
Cash from financing18.436.2-448n/a
Depreciation and amortisation14.513.913.8+4.9%
Share-based compensation79.186.6108-26.9%
Diluted shares, weighted138m138m137m+0.5%
Shares outstanding at period end134m134m132m+1.6%

Cash flow lines for the quarter; where the company files them year to date, the quarter is the difference between two filings.

Balance sheet at quarter end

LineQ3 FY2026Q2 FY2026Q3 FY2025Change on the year
Shareholders' equity3,6041,354234+1440.8%
Debt1,0131,0111,040-2.7%
Operating lease liabilities203210223-9.0%
Other liabilities3,1752,9833,354-5.3%
Total liabilities and equity7,9955,5594,852+64.8%
Fixed assets615554502+22.6%
Investments1,8331,6001,234+48.5%
Cash and equivalents1,7541,7081,490+17.7%
Receivables1,085913965+12.5%
Inventory10697.175.4+40.5%
Other assets2,602687585+344.6%
Total assets7,9955,5594,852+64.8%

Questions

What was Alnylam Pharmaceuticals' revenue in Q3 FY2026?

Alnylam Pharmaceuticals (ALNY) reported revenue of $1.5 billion for Q3 FY2026, the quarter ended 30 September 2026, up 16.7% on the same quarter a year earlier.

How much did Alnylam Pharmaceuticals earn in Q3 FY2026?

Net income for Q3 FY2026 was $2.2 billion, up 640.5% on the year, and diluted earnings per share $15.72.

When did Alnylam Pharmaceuticals report Q3 FY2026 results?

Alnylam Pharmaceuticals filed its 10-Q for the quarter ended 30 September 2026 with the SEC on 29 October 2026.

Quarterly results, the last 20 quarters

Q4 FY2021 *Q1 FY2022Q2 FY2022Q3 FY2022Q4 FY2022 *Q1 FY2023Q2 FY2023Q3 FY2023Q4 FY2023 *Q1 FY2024Q2 FY2024Q3 FY2024Q4 FY2024 *Q1 FY2025 †Q2 FY2025Q3 FY2025Q4 FY2025 *Q1 FY2026Q2 FY2026Q3 FY2026
Revenue2592132252643353193197514404946605015935947741,2491,0971,1671,2911,458
Cost of revenue33.623.534.036.546.241.475.379.572.054.667.382.010370.2142197268208298362
Gross profit2251901912282892782436713684405934194915246321,0528299609931,096
Gross margin87%89%85%86%86%87%76%89%84%89%90%84%83%88%82%84%76%82%77%75%
R&D229170206245262231249253272261294271300265324359372365413409
SG&A186154170236210184215199198211248221295240323322325323348342
Operating income-195-147-192-258-189-150-230214-116-43.448.6-76.9-10518.1-16.2368132269231346
Operating margin-75%-69%-85%-98%-56%-47%-72%28%-26%-9%7%-15%-18%3%-2%29%12%23%18%24%
Interest expense36.842.442.641.129.929.030.030.931.335.333.334.439.038.640.244.412969.382.184.4
Pre-tax income-260-239-275-406-207-172-274151-138-63.6-11.2-109-194-41.6-35.4239161222178296
Tax raten/an/an/an/an/an/an/a2%n/an/an/an/an/an/an/a-5%-16%7%7%-633%
Net income-258-240-277-406-207-174-276148-138-65.9-16.9-112-83.8-57.5-66.32511862061642,167
Net margin-100%-113%-123%-154%-62%-55%-87%20%-31%-13%-3%-22%-14%-10%-9%20%17%18%13%149%
Diluted EPS-$2.16-$2.00-$2.29-$3.32-$1.68-$1.40-$2.21$1.15-$1.10-$0.52-$0.13-$0.87-$0.66-$0.44-$0.51$1.84$0.82$1.51$1.21$15.72
Operating cash flow-150-171-123-115-132-166-59.0359-29.8-81.512443.7-94.7-12015432516470.5327341
Capital expenditure21.917.916.116.521.613.915.917.115.313.08.04.29.19.014.312.123.321.834.769.8
Free cash flow-172-189-139-132-154-180-74.9342-45.1-94.511639.5-104-12913931314048.7292271
Shares outstanding120m121m121m123m124m124m125m125m126m126m128m129m129m130m131m132m132m133m134m134m
Filing10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q
Each quarter as filed, linked to its filing.
Read more* The fourth quarter is the full year less the first three quarters, because the company files the year and not the quarter on its own. A fourth quarter's EPS, and its diluted share count where shown, are from the company's results press release for that quarter, checked against the company's filed figures or a second data source. A quarter marked † is shown as the company last restated it in a later filing, so it compares with the quarters around it on one basis; rest on a figure for the one first filed. EPS is as filed. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and the share count are as they are. Free cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Cash flow lines filed year to date are the difference between two filings. Shares outstanding are at the period end where the balance sheet tags them, otherwise the count on the filing's cover page. A derived fourth-quarter EPS is left blank when a split in the year makes the arithmetic meaningless.

10-Q for the period ended 30 September 2026, filed 29 October 2026: the filing.