greeksoup/ stock research

AbbVie Inc.: Q2 FY2026 earnings call

What management said about Q2 FY2026, from the documents filed with the SEC on 31 July 2026: press release. Guidance figures: 1 lowered, 1 new, 1 kept. The quarter’s numbers.

Key takeaways

  • Revenue rose 10.2 percent: Worldwide net revenues were $16.990 billion, up from $15.423 billion a year earlier: 10.2 percent reported and 9.5 percent operational. Source
  • Adjusted EPS rose 22.9 percent: Adjusted diluted EPS was $3.65, against $2.97. GAAP diluted EPS was $2.03, against $0.52. Both include $0.17 per share of acquired IPR&D and milestones expense. Source
  • Skyrizi revenue grew 24 percent: Skyrizi net revenues were $5.505 billion, up 24.4 percent reported and 24.0 percent operational. Source
  • Full-year adjusted EPS range lowered: The full-year 2026 adjusted diluted EPS range moved to $13.87 to $14.07, from $13.91 to $14.11, a $0.04 change at the midpoint. Source
  • Apogee dilution of $0.14 per share: The proposed Apogee acquisition is expected to dilute 2026 adjusted diluted EPS by $0.14 per share, based on an anticipated third-quarter close. Source
  • Year-to-date IPR&D cost $0.58: Full-year guidance includes $0.58 per share of acquired IPR&D and milestones expense incurred through the second quarter. Later expense is not included. Source
  • Apogee definitive agreement signed: AbbVie agreed to acquire Apogee and its clinical-stage pipeline in inflammatory and immunological diseases, including zumilokibart (APG777) and APG273. Source

“AbbVie delivered another excellent quarter, marked by outstanding execution and pipeline advancement.”

Robert A. Michael, chairman and chief executive officer, AbbVie

Guidance

AreaPeriodFigureAgainst last quarter
Adjusted diluted EPS, full year Sourcefull year 2026$13.87 - $14.07Lowered from $13.91 - $14.11
Apogee acquisition effect on adjusted EPS Sourcefull year 2026$0.14 per share dilutiveNew
Overperformance offsetting Apogee dilution Sourcefull year 2026$0.10 per share
Acquired IPR&D and milestones expense in guidance Sourceyear-to-date through second quarter 2026$0.58 per share unfavorableKept

What changed from last quarter

  • Guidance lowered: Full-year 2026 adjusted diluted EPS range moved from $13.91 to $14.11 to $13.87 to $14.07, including the Apogee dilution. Source
  • New: AbbVie agreed to acquire Apogee Therapeutics under a definitive agreement, deepening its immunology portfolio. Source
  • New: FDA approved Decnupaz, the first antibody-drug conjugate approved for blood cancer from AbbVie. Source

Second-quarter results and growth

  • Revenue rose 10.2 percent: Worldwide net revenues were $16.990 billion, up from $15.423 billion a year earlier: 10.2 percent reported and 9.5 percent operational. Source
  • Adjusted EPS rose 22.9 percent: Adjusted diluted EPS was $3.65, against $2.97. GAAP diluted EPS was $2.03, against $0.52. Both include $0.17 per share of acquired IPR&D and milestones expense. Source
  • Specified items widened the GAAP gap: Intangible asset amortization of $1,689 million pre-tax and a $1,518 million change in fair value of contingent consideration were excluded from adjusted results. Source
  • Reported against prior guidance range: The previous press release had given a second-quarter adjusted diluted EPS range of $3.57 to $3.61, including $291 million of IPR&D and milestones expense.

Immunology and neuroscience growth

  • Immunology revenue rose 15.1 percent: Immunology revenue was $8.786 billion, up 15.1 percent reported and 14.6 percent operational. Source
  • Skyrizi revenue grew 24 percent: Skyrizi net revenues were $5.505 billion, up 24.4 percent reported and 24.0 percent operational. Source
  • Humira declined as Rinvoq grew: Rinvoq net revenues were $2.525 billion, up 24.5 percent. Humira net revenues were $756 million, down 35.9 percent reported. Source
  • Neuroscience revenue rose 20.3 percent: Neuroscience revenue was $3.228 billion, up 20.3 percent reported and 19.8 percent operational, with Vraylar at $1.071 billion and Botox Therapeutic at $1.042 billion. Source
  • Migraine and Vyalev lines grew: Qulipta reached $350 million, and Ubrelvy and Qulipta combined reached $742 million. Vyalev net revenues were $256 million. Source

“We also announced the proposed acquisition of Apogee Therapeutics, which strengthens our ability to deliver innovative medicines to patients, bolsters our immunology leadership and creates significant shareholder value”

Robert A. Michael, chairman and chief executive officer, AbbVie

Oncology and aesthetics results

  • Oncology revenue slipped 1.5 percent: Oncology revenue was $1.650 billion, down 1.5 percent reported and 2.4 percent operational. Source
  • Imbruvica sales fell 29.4 percent: Imbruvica net revenues were $532 million, down 29.4 percent. The table footnote says this reflects profit sharing for international revenues. Source
  • Elahere revenue grew 33.1 percent: Elahere net revenues were $211 million, up 33.1 percent reported and 31.8 percent operational. Source
  • Aesthetics revenue was flat: Aesthetics revenue was $1.282 billion, up 0.3 percent reported and down 0.9 percent operational, with Botox Cosmetic at $728 million and Juvederm at $245 million. Source

Margins and cost lines

  • Gross margin ratio at 74.7 percent: GAAP gross margin ratio was 74.7 percent. The adjusted gross margin ratio was 84.7 percent. Source
  • Operating margin at 37.9 percent: GAAP operating margin was 37.9 percent and adjusted operating margin was 48.3 percent. Source
  • R&D and SG&A rose in dollars: R&D expense was $2,344 million, against $2,131 million a year earlier. SG&A was $3,632 million, against $3,253 million. Source
  • IPR&D expense cost $0.17 per share: Acquired IPR&D and milestones expense was $291 million, down from $823 million a year earlier, and cost $0.17 per share in the quarter. Source
  • Interest and tax rates reported: Net interest expense was $679 million. The GAAP tax rate was 15.5 percent and the adjusted tax rate was 14.7 percent. Source

2026 guidance and Apogee effect

  • Full-year adjusted EPS range lowered: The full-year 2026 adjusted diluted EPS range moved to $13.87 to $14.07, from $13.91 to $14.11, a $0.04 change at the midpoint. Source
  • Apogee dilution of $0.14 per share: The proposed Apogee acquisition is expected to dilute 2026 adjusted diluted EPS by $0.14 per share, based on an anticipated third-quarter close. Source
  • Overperformance partly offsets dilution: Overperformance of $0.10 per share partly offsets the Apogee dilution in the updated 2026 adjusted diluted EPS guidance. Source
  • Year-to-date IPR&D cost $0.58: Full-year guidance includes $0.58 per share of acquired IPR&D and milestones expense incurred through the second quarter. Later expense is not included. Source

Approvals and pipeline data

  • Skyrizi approved for pediatric psoriatic arthritis: The FDA and EC approved Skyrizi for children six and older with moderate to severe plaque psoriasis. The FDA also approved it for pediatric psoriatic arthritis. Source
  • Decnupaz approved for rare blood cancer: FDA approved Decnupaz for adults with BPDCN. It is initiated in an outpatient setting and is AbbVie’s first ADC approved for blood cancer. Source
  • Epkinly DLBCL trial met primary endpoint: Phase 3 EPCORE DLBCL-4 topline results showed statistically significant PFS improvement for Epkinly plus lenalidomide against the comparator regimen. Source
  • Rinvoq first systemic vitiligo option in EU: The EC approved Rinvoq for adult and adolescent non-segmental vitiligo, described as the first systemic medication approved in the EU for that condition. Source
  • Blood cancer data at EHA: AbbVie presented 21 oral and poster presentations at EHA 2026, highlighting etentamig, Epkinly and Decnupaz, and a final CLL14 analysis for Venclexta. Source
  • Boey approved as rapid-onset neurotoxin: The EC and Health Canada approved Boey as the first rapid-onset, short-duration neurotoxin for moderate to severe glabellar lines in adults. Source

Apogee acquisition and capital

  • Apogee definitive agreement signed: AbbVie agreed to acquire Apogee and its clinical-stage pipeline in inflammatory and immunological diseases, including zumilokibart (APG777) and APG273. Source
  • Apogee valued at $10.9 billion: The transaction values Apogee at a total equity value of approximately $10.9 billion, and management cites mega-blockbuster peak sales potential across its pipeline. Source
  • Zumilokibart targets atopic dermatitis: Zumilokibart (APG777) is a late-stage, half-life extended antibody targeting IL-13 for atopic dermatitis. APG273 targets IL-13 and TSLP for asthma. Source
  • Other expense fell year on year: Other expense, net was $1,475 million, against $2,662 million a year earlier. The $1,518 million change in contingent consideration is excluded from adjusted results. Source
  • Diluted share count held steady: Weighted-average diluted shares were 1,771 million in both second quarters, and 1,773 million for the six months of 2026 against 1,772 million. Source

Coming up, as management said on 31 July 2026

  • Apogee expected to close: The Apogee acquisition is expected to close in the third quarter of 2026. Source

Figures management reported

FigureReported
Skyrizi net revenues Source$5.505 billion, up 24.4% reported
Rinvoq net revenues Source$2.525 billion, up 24.5% reported
Humira net revenues Source$756 million, down 35.9% reported
Vraylar net revenues Source$1.071 billion, up 18.9%
Imbruvica net revenues Source$532 million, down 29.4%
Venclexta net revenues Source$771 million, up 11.6% reported
Elahere net revenues Source$211 million, up 33.1% reported
R&D expense Source$2,344 million, 13.8% of net revenues (GAAP)
Acquired IPR&D and milestones expense Source$291 million in the quarter
Approvals SourceDecnupaz (FDA); Skyrizi pediatric (FDA and EC); Rinvoq (EC, vitiligo and alopecia areata); Boey (EC and Health Canada)
Trial readout SourceEPCORE DLBCL-4 topline, PFS improved

Risks management discussed

  • Financial: Acquired IPR&D and milestones expense cannot be reliably forecast, so guidance excludes any such expense beyond the second quarter. Source

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.