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<title>Septerna, Inc. (SEPN) on GreekSoup</title>
<link>https://greeksoup.ai/stocks/us/sepn/</link>
<description>Every dated entry in the public record on Septerna, Inc.: results, filings, insider trades and the rest, from the filings, the last 90 days.</description>
<language>en</language>
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<lastBuildDate>Wed, 28 Oct 2026 00:00:00 +0000</lastBuildDate>
<item><title>Septerna, Inc.: Bhatt Elizabeth (President and COO) sold 1,094 shares (under a trading plan set in advance) at $36.87 on 15 October 2026, $40,337</title><link>https://greeksoup.ai/stocks/us/sepn/insiders/</link><guid isPermaLink="false">us:SEPN:insider:2026-10-19:83afcae1b3</guid><pubDate>Mon, 19 Oct 2026 00:00:00 +0000</pubDate><category>Insider trade</category><description><![CDATA[<p>Insider trade. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000119312526425485/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/insiders/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Bhatt Elizabeth (President and COO) sold 2,906 shares (under a trading plan set in advance) at $37.61 on 15 October 2026, $109,307</title><link>https://greeksoup.ai/stocks/us/sepn/insiders/</link><guid isPermaLink="false">us:SEPN:insider:2026-10-19:cb1741248a</guid><pubDate>Mon, 19 Oct 2026 00:00:00 +0000</pubDate><category>Insider trade</category><description><![CDATA[<p>Insider trade. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000119312526425485/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/insiders/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: short interest 3,522,956 shares at the 15 October 2026 settlement, 7.63 days to cover</title><link>https://greeksoup.ai/stocks/us/sepn/short-interest/</link><guid isPermaLink="false">us:SEPN:short-interest:2026-10-15:cddc3d1b60</guid><pubDate>Thu, 15 Oct 2026 00:00:00 +0000</pubDate><category>Short interest</category><description><![CDATA[<p>Short interest. <a href="https://www.finra.org/finra-data/browse-catalog/equity-short-interest/data">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/short-interest/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Form 144, DANIEL LONG plans to sell 10,001 shares worth $391,339 around 1 October 2026</title><link>https://greeksoup.ai/stocks/us/sepn/planned-sales/</link><guid isPermaLink="false">us:SEPN:planned-sale:2026-10-01:f11a12088b</guid><pubDate>Thu, 01 Oct 2026 00:00:00 +0000</pubDate><category>Form 144</category><description><![CDATA[<p>Form 144. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000195004726009973/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/planned-sales/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Form 144, SAMIRA SHAIKHLY plans to sell 12,592 shares worth $492,725 around 1 October 2026</title><link>https://greeksoup.ai/stocks/us/sepn/planned-sales/</link><guid isPermaLink="false">us:SEPN:planned-sale:2026-10-01:f8436d73ae</guid><pubDate>Thu, 01 Oct 2026 00:00:00 +0000</pubDate><category>Form 144</category><description><![CDATA[<p>Form 144. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000195004726009949/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/planned-sales/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: short interest 3,096,190 shares at the 30 September 2026 settlement, 8.80 days to cover</title><link>https://greeksoup.ai/stocks/us/sepn/short-interest/</link><guid isPermaLink="false">us:SEPN:short-interest:2026-09-30:68f76c9705</guid><pubDate>Wed, 30 Sep 2026 00:00:00 +0000</pubDate><category>Short interest</category><description><![CDATA[<p>Short interest. <a href="https://www.finra.org/finra-data/browse-catalog/equity-short-interest/data">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/short-interest/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: short interest 2,894,002 shares at the 15 September 2026 settlement, 9.54 days to cover</title><link>https://greeksoup.ai/stocks/us/sepn/short-interest/</link><guid isPermaLink="false">us:SEPN:short-interest:2026-09-15:94d39c5da7</guid><pubDate>Tue, 15 Sep 2026 00:00:00 +0000</pubDate><category>Short interest</category><description><![CDATA[<p>Short interest. <a href="https://www.finra.org/finra-data/browse-catalog/equity-short-interest/data">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/short-interest/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Long Daniel D. (SVP, Drug Discovery) sold 3,333 shares (under a trading plan set in advance) at $37.83 on 1 September 2026, $126,078</title><link>https://greeksoup.ai/stocks/us/sepn/insiders/</link><guid isPermaLink="false">us:SEPN:insider:2026-09-03:65b403bf1a</guid><pubDate>Thu, 03 Sep 2026 00:00:00 +0000</pubDate><category>Insider trade</category><description><![CDATA[<p>Insider trade. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000119312526382267/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/insiders/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: short interest 2,718,332 shares at the 31 August 2026 settlement, 7.65 days to cover</title><link>https://greeksoup.ai/stocks/us/sepn/short-interest/</link><guid isPermaLink="false">us:SEPN:short-interest:2026-08-31:6c01dd60f4</guid><pubDate>Mon, 31 Aug 2026 00:00:00 +0000</pubDate><category>Short interest</category><description><![CDATA[<p>Short interest. <a href="https://www.finra.org/finra-data/browse-catalog/equity-short-interest/data">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/short-interest/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc. filed 8-K: regulation fd disclosure, other events</title><link>https://greeksoup.ai/stocks/us/sepn/filings/</link><guid isPermaLink="false">us:SEPN:filing:2026-08-25:e6c434ff2b</guid><pubDate>Tue, 25 Aug 2026 00:00:00 +0000</pubDate><category>SEC filing</category><description><![CDATA[<p>SEC filing. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000119312526364210/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/filings/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Schedule 13D/A filed by RA Capital Management, L.P., 11.8% of the class</title><link>https://greeksoup.ai/stocks/us/sepn/holders/</link><guid isPermaLink="false">us:SEPN:schedule-13:2026-08-14:63bef9d64e</guid><pubDate>Fri, 14 Aug 2026 00:00:00 +0000</pubDate><category>Schedule 13D/13G</category><description><![CDATA[<p>Schedule 13D/13G. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000134682426000228/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/holders/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Schedule 13G/A filed by DRIEHAUS CAPITAL MANAGEMENT LLC, 9.8% of the class</title><link>https://greeksoup.ai/stocks/us/sepn/holders/</link><guid isPermaLink="false">us:SEPN:schedule-13:2026-08-14:94cc6034af</guid><pubDate>Fri, 14 Aug 2026 00:00:00 +0000</pubDate><category>Schedule 13D/13G</category><description><![CDATA[<p>Schedule 13D/13G. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000093820626000037/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/holders/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Third Rock Ventures V, L.P. (10% owner) sold 147,059 shares (under a trading plan set in advance) at $50.27 on 12 August 2026, $7.4 million</title><link>https://greeksoup.ai/stocks/us/sepn/insiders/</link><guid isPermaLink="false">us:SEPN:insider:2026-08-14:46e3bfb9b0</guid><pubDate>Fri, 14 Aug 2026 00:00:00 +0000</pubDate><category>Insider trade</category><description><![CDATA[<p>Insider trade. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000119312526352692/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/insiders/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Third Rock Ventures V, L.P. (10% owner) sold 141 shares (under a trading plan set in advance) at $51.08 on 12 August 2026, $7,202</title><link>https://greeksoup.ai/stocks/us/sepn/insiders/</link><guid isPermaLink="false">us:SEPN:insider:2026-08-14:b62d5d87c5</guid><pubDate>Fri, 14 Aug 2026 00:00:00 +0000</pubDate><category>Insider trade</category><description><![CDATA[<p>Insider trade. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000119312526352692/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/insiders/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Ra Capital Management, L.P. (Director), see footnotes, sold 746,500 shares at $42.50 on 12 August 2026, $31.7 million</title><link>https://greeksoup.ai/stocks/us/sepn/insiders/</link><guid isPermaLink="false">us:SEPN:insider:2026-08-14:95b9b062fb</guid><pubDate>Fri, 14 Aug 2026 00:00:00 +0000</pubDate><category>Insider trade</category><description><![CDATA[<p>Insider trade. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000123191926000938/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/insiders/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Ra Capital Management, L.P. (Director), see footnotes, sold 746,500 shares at $42.50 on 12 August 2026, $31.7 million</title><link>https://greeksoup.ai/stocks/us/sepn/insiders/</link><guid isPermaLink="false">us:SEPN:insider:2026-08-14:95b9b062fb</guid><pubDate>Fri, 14 Aug 2026 00:00:00 +0000</pubDate><category>Insider trade</category><description><![CDATA[<p>Insider trade. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000123191926000938/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/insiders/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: short interest 2,874,690 shares at the 14 August 2026 settlement, 5.06 days to cover</title><link>https://greeksoup.ai/stocks/us/sepn/short-interest/</link><guid isPermaLink="false">us:SEPN:short-interest:2026-08-14:b931752288</guid><pubDate>Fri, 14 Aug 2026 00:00:00 +0000</pubDate><category>Short interest</category><description><![CDATA[<p>Short interest. <a href="https://www.finra.org/finra-data/browse-catalog/equity-short-interest/data">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/short-interest/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Bhatt Elizabeth (President and COO) sold 25,000 shares (under a trading plan set in advance) at $44.00 on 11 August 2026, $1.1 million</title><link>https://greeksoup.ai/stocks/us/sepn/insiders/</link><guid isPermaLink="false">us:SEPN:insider:2026-08-13:6887857b33</guid><pubDate>Thu, 13 Aug 2026 00:00:00 +0000</pubDate><category>Insider trade</category><description><![CDATA[<p>Insider trade. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000119312526349810/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/insiders/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Form 144, Third Rock Ventures V, L.P. plans to sell 147,200 shares worth $7.5 million around 12 August 2026</title><link>https://greeksoup.ai/stocks/us/sepn/planned-sales/</link><guid isPermaLink="false">us:SEPN:planned-sale:2026-08-12:a6337876dc</guid><pubDate>Wed, 12 Aug 2026 00:00:00 +0000</pubDate><category>Form 144</category><description><![CDATA[<p>Form 144. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000197407826000301/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/planned-sales/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Form 144, RA Capital Healthcare Fund LP plans to sell 746,500 shares worth $36.0 million around 12 August 2026</title><link>https://greeksoup.ai/stocks/us/sepn/planned-sales/</link><guid isPermaLink="false">us:SEPN:planned-sale:2026-08-12:587e5f2e30</guid><pubDate>Wed, 12 Aug 2026 00:00:00 +0000</pubDate><category>Form 144</category><description><![CDATA[<p>Form 144. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000117893726000042/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/planned-sales/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Form 144, RA Capital Nexus Fund III, L.P. plans to sell 746,500 shares worth $36.0 million around 12 August 2026</title><link>https://greeksoup.ai/stocks/us/sepn/planned-sales/</link><guid isPermaLink="false">us:SEPN:planned-sale:2026-08-12:9bb9eb6084</guid><pubDate>Wed, 12 Aug 2026 00:00:00 +0000</pubDate><category>Form 144</category><description><![CDATA[<p>Form 144. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000117893726000041/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/planned-sales/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Form 144, ELIZABETH P. BHATT plans to sell 29,000 shares worth $1.1 million around 11 August 2026</title><link>https://greeksoup.ai/stocks/us/sepn/planned-sales/</link><guid isPermaLink="false">us:SEPN:planned-sale:2026-08-11:35c3196800</guid><pubDate>Tue, 11 Aug 2026 00:00:00 +0000</pubDate><category>Form 144</category><description><![CDATA[<p>Form 144. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000195004726007956/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/planned-sales/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc. Q2 FY2026 results: revenue $27 million, net income -$13 million</title><link>https://greeksoup.ai/stocks/us/sepn/results/fy2026-q2/</link><guid isPermaLink="false">us:SEPN:result:2026-08-10:9f0000ec1e</guid><pubDate>Mon, 10 Aug 2026 00:00:00 +0000</pubDate><category>Results</category><description><![CDATA[<p>Results. <a href="https://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&amp;CIK=0001984086&amp;type=10-&amp;dateb=&amp;owner=include&amp;count=40">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/results/fy2026-q2/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc. filed 10-Q: 10-q</title><link>https://greeksoup.ai/stocks/us/sepn/filings/</link><guid isPermaLink="false">us:SEPN:filing:2026-08-10:40a3db461d</guid><pubDate>Mon, 10 Aug 2026 00:00:00 +0000</pubDate><category>SEC filing</category><description><![CDATA[<p>SEC filing. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000119312526342353/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/filings/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc. filed 8-K: results of operations</title><link>https://greeksoup.ai/stocks/us/sepn/filings/</link><guid isPermaLink="false">us:SEPN:filing:2026-08-10:9421ba2f5a</guid><pubDate>Mon, 10 Aug 2026 00:00:00 +0000</pubDate><category>SEC filing</category><description><![CDATA[<p>SEC filing. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000119312526342328/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/filings/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Long Daniel D. (SVP, Drug Discovery) sold 1,000 shares (under a trading plan set in advance) at $33.98 on 3 August 2026, $33,976</title><link>https://greeksoup.ai/stocks/us/sepn/insiders/</link><guid isPermaLink="false">us:SEPN:insider:2026-08-05:889ac4a71e</guid><pubDate>Wed, 05 Aug 2026 00:00:00 +0000</pubDate><category>Insider trade</category><description><![CDATA[<p>Insider trade. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000119312526335820/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/insiders/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: Long Daniel D. (SVP, Drug Discovery) sold 2,334 shares (under a trading plan set in advance) at $34.68 on 3 August 2026, $80,944</title><link>https://greeksoup.ai/stocks/us/sepn/insiders/</link><guid isPermaLink="false">us:SEPN:insider:2026-08-05:282e72d354</guid><pubDate>Wed, 05 Aug 2026 00:00:00 +0000</pubDate><category>Insider trade</category><description><![CDATA[<p>Insider trade. <a href="https://www.sec.gov/Archives/edgar/data/1984086/000119312526335820/">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/insiders/">The page on GreekSoup</a>.</p>]]></description></item>
<item><title>Septerna, Inc.: short interest 3,507,965 shares at the 31 July 2026 settlement, 14.15 days to cover</title><link>https://greeksoup.ai/stocks/us/sepn/short-interest/</link><guid isPermaLink="false">us:SEPN:short-interest:2026-07-31:426fbc131d</guid><pubDate>Fri, 31 Jul 2026 00:00:00 +0000</pubDate><category>Short interest</category><description><![CDATA[<p>Short interest. <a href="https://www.finra.org/finra-data/browse-catalog/equity-short-interest/data">The filing</a>. <a href="https://greeksoup.ai/stocks/us/sepn/short-interest/">The page on GreekSoup</a>.</p>]]></description></item>
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